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Stress Response and Anxiolytic Models: In rodent elevated plus-maze
stress-axis modulation
non-selective agonist of the estrogen-related receptors (ERRs)
It functions by binding to HDM-2
ACE-031 Stress Response and Anxiolytic Models:Overview ACE 031, also known as ramatercept or ACVR2B Fc, is a recombinant fusion protein consisting of the extracellular domain of human activin receptor type IIB (ActRIIB) fused to the Fc portion of human IgG1. It functions as a soluble decoy receptor that binds myostatin (GDF 8) and other TGF superfamily ligands (activins, GDF 11), preventing their interaction with endogenous receptors. It is widely used in laboratory and preclinical research as a
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