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little activity against IGF-1R
PD318088 is a non-ATP competitive allosteric MEK1/2 inhibitor
Nitrofural is a topical anti-infective agent with an IC50 of 22
The MWLH series is designed to be incorporated into the customer's weighing
Raltegravir (MK-0518) Extra little activity against IGF-1RRaltegravir (MK 0518) is a potent integrase (IN) inhibitor for WT and S217Q PFV IN with IC50 of 90 nM and 40 nM in cell free assays, respectively. It shows greater than 1000 fold selectivity for HIV 1 IN over several related Mg2+ dependent enzyme such as HCV polymerase, HIV reverse transcriptase, HIV RNaseH and human ? , ? , ? polymerases.
