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Published 2021 Mar 17
[Accession | P32971]
Q: What is the binding mechanism of YeaRed
ELISA Data: Immobilized Human PLAU
MG132 (MG-132) _ 52801ES INF Published 2021 Mar 17MG132 is a potent, reversible, cell permeable proteasome inhibitor (IC50=100 nM), more than 1000 fold more potent than ZLLal in inhibiting the ZLLL MCA degradation activity of the 20S proteasome. MG132 also inhibits the cell cycle and calpain required for cyclin degradation (IC50=1. 2 M), and induces neurite outgrowth in PC12 cells. In addition, MG132 inhibited IB degradation, thereby inhibiting NF B pathway activation. MG132 induces apoptosis of MPM
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