Mal-Propionyl-Dap(m-PEG4)-Val-Ala-PAB Alexa Fluor 488 525 SMILES: CN(C)C1=CC=C2C(OC3=CC(C=CC3=C2C2=CC(=CC=C2C([O-])=O)C(=O)NCC#C)=[N+](C)C)=C1 Purity (HPLC):

525 SMILES: CN(C)C1=CC=C2C(OC3=CC(C=CC3=C2C2=CC(=CC=C2C([O-])=O)C(=O)NCC#C)=[N+](C)C)=C1 Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only

26 SMILES CC1(N)CCN(CC1)C1=CN=C(C(N)=N1)C1=C(Cl)C(Cl)=CC=C1 Purity (HPLC) >= 95% Physical Appearance White solid Solubility DMSO

and cell membrane permeability

Product Name Mal-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-Exatecan Synonyms CAS Number Related CAS Molecular Formula C77H96FN11O23 Molecular Weight 1562

Mal-Propionyl-Dap(m-PEG4)-Val-Ala-PAB Alexa Fluor 488 525 SMILES: CN(C)C1=CC=C2C(OC3=CC(C=CC3=C2C2=CC(=CC=C2C([O-])=O)C(=O)NCC#C)=[N+](C)C)=C1 Purity (HPLC):SOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a Mal Propionyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine containing groups, or polysarcosine