Mal-Propionyl-PEG4-Gly-Gly-Phe-Gly-PAB(m-PEG4)-Exatecan clip This dual reactivity forces the

This dual reactivity forces the tagged proteins into close proximity

Product Name DOTA-PEG4-C2-amine Synonyms CAS Number 2090232-34-9 Related CAS Molecular Formula C26H50N6O11 Molecular Weight 622

349 SMILES OC(=O)CCCCOC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

planar structure around the boron-dipyrromethene core imparts exceptional photostability

Mal-Propionyl-PEG4-Gly-Gly-Phe-Gly-PAB(m-PEG4)-Exatecan clip This dual reactivity forces theSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG4 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent