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DBCO-Hexanoyl-Val-Ala-PAB(m-PEG8)-Exatecan Size:1mg ZXH-1-161 can be used for

SKU: 84836984913

4.9
USD445.00 USD476.00

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Description

ZXH-1-161 can be used for researching multiple myeloma

Product Name 5-FAM PEG3 alkyne Synonyms CAS Number N/A Related CAS Molecular Formula C30H27NO9 Molecular Weight 545

Product Name ispinesib Synonyms 8F20

613 Purity (HPLC) >= 95% Solubility DMSO

DBCO-Hexanoyl-Val-Ala-PAB(m-PEG8)-Exatecan Size:1mg ZXH-1-161 can be used forSOLU KNEX cleavable linker features a Val Ala dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC

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