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Fmoc-Val-Ala-PAB(m-PEG4)-PNP linker The payload is Exatecan

SKU: 61873590467

4.4
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Description

The payload is Exatecan

Product Name DOTA-C4-alcohol Synonyms CAS Number n/a Related CAS Molecular Formula C20H37N5O8 Molecular Weight 475

Product Name Lenalidomide-C4-acid Synonyms Lenalidomide-4'-C4-acid CAS Number 2338824-29-4 Related CAS Molecular Formula C18H21N3O5 Molecular Weight 359

263 SMILES BrCCOCCCC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Fmoc-Val-Ala-PAB(m-PEG4)-PNP linker The payload is ExatecanSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine containing groups, or polysarcosine (PSAR), to enhance aqueous solubility. Solubility and physicochemical properties can be finely tuned

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