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Wong-Dilworth
1038/35104500
486 SMILES: NCCCCCNC(=O)C1=CC=C2C(=C1)C(=O)OC21C2=CC=C(O)C=C2OC2=C1C=CC(O)=C2 Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only
Product Name BG-FAM Synonyms SNAP-FAM CAS Number 1154528-97-8 Related CAS Molecular Formula C34H24N6O7 Molecular Weight 628
Mal-Propionyl-Beta-Ala-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE Size:10mg Wong-DilworthSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers
