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NRX-252262 acts as molecular glue in cells to promote the ubiquitylation and subsequent degradation of mutantbeta-catenin by the 26S proteasome
It stabilizes the noncovalent CDC34A-donor ubiquitin complex
Product Name Thalidomide-O-acetamido-PEG2-propargyl Synonyms Thalidomide-4'-O-acetamido-PEG2-propargyl CAS Number n/a Related CAS Molecular Formula C22H23N3O8 Molecular Weight 457
34 SMILES OCCCCC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
DOTA-tris(t-Bu)ester-hexyne Size:5mg NRX-252262 acts as molecular glueDOTA bifucational chelator containing an alkyne group, an alkyl linker, and the macrocyclic chelator DOTA ( 1,4,7,10 tetraazacyclododecane 1,4,7,10 tetraacetic acid). It can be used in many different diagnostic and therapeutic applications, such as MRI contrast agents, PET and SPECT imaging agents, and radiotherapeutic agents. Product Name DOTA tris(t Bu)ester hexyne Synonyms CAS Number n a Related CAS Molecular Formula C34H61N5O7 Molecular Weight
