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Mal-Propionyl-PEG8-Gly-Gly-Phe-Gly-PAB(m-PEG4) deuterium-labeled-amine As a negative control

SKU: 35118147705

4.8
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Description

As a negative control

VHL-SNAP2-5C is a SNAP PROteolysis TArgeting Chimera (SNAP-PROTAC)

037 Purity (HPLC) >= 95% Solubility DMSO

Product Name 4-bromo-3-(methoxy-d3)-benzaldehyde Synonyms CAS Number n/a Related CAS Molecular Formula C8H7BrO2 Molecular Weight 218

Mal-Propionyl-PEG8-Gly-Gly-Phe-Gly-PAB(m-PEG4) deuterium-labeled-amine As a negative controlSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG8 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker

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