Azide-Hexanoyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE dbco 148 Purity (HPLC) >= 95%

148 Purity (HPLC) >= 95% Solubility DMSO

8 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCOCCOCCC(O)=O)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name Thalidomide-C4-OH Synonyms Thalidomide-4'-C4-OH CAS Number n/a Related CAS Molecular Formula C17H18N2O5 Molecular Weight 330

301 SMILES OCCNC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Azide-Hexanoyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE dbco 148 Purity (HPLC) >= 95%SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate