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and Orally Bioavailable Small-Molecule GSPT1/2 Degraders from a Focused Library of Cereblon Modulators
BI-3802 has antitumor activity
Product Name: 5-FAM Synonyms: 5-Carboxyfluorescein CAS Number: 76823-03-5 Molecular Formula: C21H12O7 Molecular Weight: 376
the labeling efficiency of tetramethylrhodamine maleimides and iodoacetamides is often lower compared to that of other tetramethylrhodamine labeling dyes
Azide-Dap(m-PEG4)-Val-Ala-PAB(m-PEG8)-MMAE Size:1mg and Orally Bioavailable Small-Molecule GSPT1/2SOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a Azide Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The azide functional group is widely utilized in bioconjugation via click chemistry to enable efficient and selective attachment of biomolecules. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase
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