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SiR (silicon-rhodamine) dyes are a family of far-red fluorescent probes derived from a modified rhodamine structure in which oxygen is replaced with silicon
927 Purity (HPLC) >= 95% Solubility DMSO
NCCCCNC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
Endogenous tagging enabled the visualization and the selective depletion of a SNAP-clathrin light chain fusion protein using SNAP-PROTACs
DBCO-Propionyl-Val-Cit-PAB(m-PEG8)-MMAE Size:25mg SiR (silicon-rhodamine) dyes are aSOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing
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