Mal-Propionyl-PEG4-Val-Cit-PAB(m-PEG4)-Exatecan Size:5mg S)-AHPC-acetamido-O-propargyl Synonyms CAS Number 2098799-78-9

S)-AHPC-acetamido-O-propargyl Synonyms CAS Number 2098799-78-9 Related CAS Molecular Formula C27H34N4O5S Molecular Weight 526

Product Name Sulfo-CA-Lissamine Rhodamine B Synonyms Lissamine Rhodamine B Halotag Ligand Impermeable CAS Number N/A Related CAS N/A Molecular Formula C40H55ClN3O11S3 Molecular Weight 885

Product Name Thalidomide-O-PEG3-C2-azide Synonyms Thalidomide-4'-O-PEG3-C2-azide CAS Number 2758432-01-6 Related CAS Molecular Formula C21H25N5O8 Molecular Weight 475

406 SMILES [N-]=[N+]=NCCCCCC(=O)NC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Mal-Propionyl-PEG4-Val-Cit-PAB(m-PEG4)-Exatecan Size:5mg S)-AHPC-acetamido-O-propargyl Synonyms CAS Number 2098799-78-9SOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG4 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I