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Mindbreak Trap does a few things exceptionally, both shutting off certain kinds of combo deck engine and dealing with uncounterable spells such as Obliterate

It does best in mono-green, of course, but I could see running it in a 2-color deck

In other words, youll be able to make 90% of the designs you have in mind here, but some of your fancier, more outlandish card designs probably dont have a compatible card frame

It's around #14 or 15 on my list and not in the Top 10 proper, but the ability to force someone to discard, and destroy artifacts and critters with one number is a very precise scalpel that destroys what you need, but tends to leave your own stuff alone